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Rajagiri Hospital Successfully Performs Advanced CAR T-Cell Therapy for Lymphoma

Kochi: In a significant breakthrough for cancer care in Kerala, doctors at Rajagiri Hospital, Aluva, have successfully performed CAR T-cell (Chimeric Antigen Receptor T-cell) therapy on a 64-year-old patient from Puthenvelikkara diagnosed with Lymphoma. This advanced "living drug" treatment marks another milestone for the hospital in providing cutting-edge solutions for complex cancers that do not respond to conventional chemotherapy. The procedure was led by Dr. Roy J. Palatty and Dr. Nikhil M. Kumar from the Department of Clinical Hematology at the Rajagiri Cancer Centre.

CAR T-cell therapy is a revolutionary form of immunotherapy that genetically modifies a patient's own immune system to target and destroy cancer. The process begins with the collection of T-cells from the patient’s blood using a sophisticated apheresis machine, which separates specific blood components in real-time. These cells are then sent to a specialized laboratory where they are genetically engineered to produce receptors called Chimeric Antigen Receptors (CARs). Once re-infused into the patient, these "supercharged" cells specifically identify and eliminate cancer cells while sparing healthy tissue.

According to Dr. Roy J. Palatty, the primary advantage of this procedure is that it is a one-time treatment with relatively fewer side effects and a shorter hospital stay compared to traditional methods. Furthermore, the risk of the disease returning is significantly lower. Dr. Nikhil M. Kumar highlighted that while this treatment was previously exorbitant and required patients to travel abroad, the development of CAR T-cell technology within India has made it far more affordable and accessible. Fr. Johnson Vazhappilly, Executive Director of Rajagiri Hospital, congratulated the clinical team for their consistent success and commitment to medical excellence in the field of oncology.

26 Mar 2026 Back

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